PINK1 Deficiency Ameliorates Cisplatin-Induced Acute Kidney Injury in Rats

Mitophagy plays a key role in cleaning damaged and depolarized mitochondria to maintain cellular homeostasis and viability. Although it was originally found in neurodegenerative diseases, mitophagy is reported to play an important role in acute kidney injury. PINK1 and Parkin are key molecules in mi...

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Bibliographic Details
Main Authors: Li Zhou, Ling Zhang, Yu Zhang, Xuan Yu, Xiuping Sun, Tao Zhu, Xianglei Li, Wei Liang, Yunlin Han, Chuan Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01225/full