P2X7 Receptor Inhibition Improves CD34 T-Cell Differentiation in HIV-Infected Immunological Nonresponders on c-ART.

P2X7 Receptor Inhibition Improves CD34 T-Cell Differentiation in HIV-Infected Immunological Nonresponders on c-ART.

Peripheral CD4+ T-cell levels are not fully restored in a significant proportion of HIV+ individuals displaying long-term viral suppression on c-ART. These immunological nonresponders (INRs) have a higher risk of developing AIDS and non-AIDS events and a lower life expectancy than the general popula...

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Bibliographic Details
Main Authors: Inna Menkova-Garnier, Hakim Hocini, Emile Foucat, Pascaline Tisserand, Laure Bourdery, Constance Delaugerre, Clarisse Benne, Yves Lévy, Jean-Daniel Lelièvre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4833302?pdf=render

Internet

http://europepmc.org/articles/PMC4833302?pdf=render

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