Sugar Responses of Human Enterochromaffin Cells Depend on Gut Region, Sex, and Body Mass

Sugar Responses of Human Enterochromaffin Cells Depend on Gut Region, Sex, and Body Mass

Gut-derived serotonin (5-HT) is released from enterochromaffin (EC) cells in response to nutrient cues, and acts to slow gastric emptying and modulate gastric motility. Rodent studies also evidence a role for gut-derived 5-HT in the control of hepatic glucose production, lipolysis and thermogenesis,...

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Bibliographic Details
Main Authors: Amanda L. Lumsden, Alyce M. Martin, Emily W. Sun, Gudrun Schober, Nicole J. Isaacs, Nektaria Pezos, David A. Wattchow, Dayan de Fontgalland, Philippa Rabbitt, Paul Hollington, Luigi Sposato, Steven L. Due, Christopher K. Rayner, Nam Q. Nguyen, Alice P. Liou, V. Margaret Jackson, Richard L. Young, Damien J. Keating
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Nutrients
Subjects:
serotonin
5-hydroxytryptamine
5-HT
glucose
enterochromaffin
obesity
duodenum
colon
Online Access:https://www.mdpi.com/2072-6643/11/2/234

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https://www.mdpi.com/2072-6643/11/2/234

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