Clinical applications of microRNAs [v2; ref status: indexed, http://f1000r.es/1o3]
MicroRNAs represent a class of small RNAs derived from polymerase II controlled transcriptional regions. The primary transcript forms one or several bulging double stranded hairpins which are processed by Drosha and Dicer into hetero-duplexes. The targeting microRNA strand of the duplex is incorpora...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2013-08-01
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Series: | F1000Research |
Subjects: | |
Online Access: | http://f1000research.com/articles/2-136/v2 |