An increase in CD3+CD4+CD25+ regulatory T cells after administration of umbilical cord-derived mesenchymal stem cells during sepsis.

Sepsis remains an important cause of death worldwide, and vigorous immune responses during sepsis could be beneficial for bacterial clearance but at the price of collateral damage to self tissues. Mesenchymal stem cells (MSCs) have been found to modulate the immune system and attenuate sepsis. In th...

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Bibliographic Details
Main Authors: Yu-Hua Chao, Han-Ping Wu, Kang-Hsi Wu, Yi-Giien Tsai, Ching-Tien Peng, Kuan-Chia Lin, Wan-Ru Chao, Maw-Sheng Lee, Yun-Ching Fu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4206342?pdf=render