Theaflavin-3, 3′-digallate, a black tea polyphenol, attenuates adipocyte-activated inflammatory response of macrophage associated with the switch of M1/M2-like phenotype

The paracrine-loop of hypertrophic adipocytes and macrophages in adipose tissue mediates chronic inflammation state (metaflammation) that closely links to disease development in obesity. We investigated the metaflammation-preventing effect of theaflavin-3, 3′-digallate (TF3) in a transwell-co-cultur...

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Bibliographic Details
Main Authors: Huey-Jiun Ko, Chih-Yu Lo, Be-Jen Wang, Robin Yih-Yuan Chiou, Shu-Mei Lin
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464614002874