APOC1 T45S polymorphism is associated with reduced obesity indices and lower plasma concentrations of leptin and apolipoprotein C-I in aboriginal Canadians

APOC1 T45S polymorphism is associated with reduced obesity indices and lower plasma concentrations of leptin and apolipoprotein C-I in aboriginal Canadians

Apolipoprotein (apo) C-I is a constituent of chylomicrons, very low density lipoprotein, and high density lipoprotein. The role of apo C-I in human metabolism is incompletely defined. We took advantage of a naturally occurring amino acid polymorphism that is present in aboriginal North Americans, na...

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Bibliographic Details
Main Authors: Piya Lahiry, Henian Cao, Matthew R. Ban, Rebecca L. Pollex, Mary Mamakeesick, Bernard Zinman, Stewart B. Harris, Anthony J.G. Hanley, Murray W. Huff, Philip W. Connelly, Robert A. Hegele
Format: Article
Language:English
Published: Elsevier 2010-04-01
Series:Journal of Lipid Research
Subjects:
nonsynonymous variant
leptin
Canadian First Nation population
genetics
serum levels
hypertriglyceridemic waist
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520304946

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http://www.sciencedirect.com/science/article/pii/S0022227520304946

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