Transcriptomic heterogeneity of driver gene mutations reveals novel mutual exclusivity and improves exploration of functional associations

Transcriptomic heterogeneity of driver gene mutations reveals novel mutual exclusivity and improves exploration of functional associations

Abstract Background Lung adenocarcinoma (LUAD), as the most common subtype of lung cancer, is the leading cause of cancer deaths in the world. The accumulation of driver gene mutations enables cancer cells to gradually acquire growth advantage. Therefore, it is important to understand the functions...

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Bibliographic Details
Main Authors: Yujia Lan, Wei Liu, Wanmei Zhang, Jing Hu, Xiaojing Zhu, Linyun Wan, Suru A, Yanyan Ping, Yun Xiao
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Cancer Medicine
Subjects:
mutations
functional associations
mutual exclusivity
non small cell lung cancer
cancer genetics
Online Access:https://doi.org/10.1002/cam4.4039

Internet

https://doi.org/10.1002/cam4.4039

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