Integrin β1 Optimizes Diabetogenic T Cell Migration and Function in the Pancreas
T cell search behavior is dictated by their need to encounter their specific antigen to eliminate target cells. However, mechanisms controlling effector T cell motility are highly tissue-dependent. Specifically, how diabetogenic T cells encounter their target beta cells in dispersed islets throughou...
Main Authors: | Gabriel Espinosa-Carrasco, Cécile Le Saout, Pierre Fontanaud, Aurélien Michau, Patrice Mollard, Javier Hernandez, Marie Schaeffer |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-05-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2018.01156/full |
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