10-Hydroxy-2-decenoic Acid, a Major Fatty Acid from Royal Jelly, Inhibits VEGF-Induced Angiogenesis in Human Umbilical Vein Endothelial Cells

Vascular endothelial growth factor (VEGF) is reported to be a potent pro-angiogenic factor that plays a pivotal role in both physiological and pathological angiogenesis. Royal jelly (RJ) is a honeybee product containing various proteins, sugars, lipids, vitamins and free amino acids. 10-Hydroxy-2-de...

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Bibliographic Details
Main Authors: Hiroshi Izuta, Yuichi Chikaraishi, Masamitsu Shimazawa, Satoshi Mishima, Hideaki Hara
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1093/ecam/nem152