Heme oxygenase 1 overexpression increases iron fluxes in Caco-2 cells
Heme oxygenase-1 is a microsomal enzyme that, when induced by stress, protects the cells from oxidative injury. Heme oxygenase-1 participates in the cleavage of the heme ring producing biliverdin, CO and ferrous Fe. The released Fe becomes part of intracellular Fe pool and can be stored in ferritin...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2006-01-01
|
Series: | Biological Research |
Subjects: | |
Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000100023 |