Heme oxygenase 1 overexpression increases iron fluxes in Caco-2 cells

Heme oxygenase-1 is a microsomal enzyme that, when induced by stress, protects the cells from oxidative injury. Heme oxygenase-1 participates in the cleavage of the heme ring producing biliverdin, CO and ferrous Fe. The released Fe becomes part of intracellular Fe pool and can be stored in ferritin...

Full description

Bibliographic Details
Main Authors: MARÍA JOSE MENDIBURO, SEBASTIÁN FLORES, FERNANDO PIZARRO, MIGUEL ARREDONDO
Format: Article
Language:English
Published: BMC 2006-01-01
Series:Biological Research
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000100023