Cytolethal distending toxin induces the formation of transient messenger-rich ribonucleoprotein nuclear invaginations in surviving cells.

Cytolethal distending toxin induces the formation of transient messenger-rich ribonucleoprotein nuclear invaginations in surviving cells.

Humans are frequently exposed to bacterial genotoxins involved in digestive cancers, colibactin and Cytolethal Distending Toxin (CDT), the latter being secreted by many pathogenic bacteria. Our aim was to evaluate the effects induced by these genotoxins on nuclear remodeling in the context of cell s...

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Bibliographic Details
Main Authors: Lamia Azzi-Martin, Wencan He, Christelle Péré-Védrenne, Victoria Korolik, Chloé Alix, Martina Prochazkova-Carlotti, Jean-Luc Morel, Emilie Le Roux-Goglin, Philippe Lehours, Mojgan Djavaheri-Mergny, Christophe F Grosset, Christine Varon, Pierre Dubus, Armelle Ménard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007921

Internet

https://doi.org/10.1371/journal.ppat.1007921

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