IgG Fc Glycosylation Patterns of Preterm Infants Differ With Gestational Age

IgG Fc Glycosylation Patterns of Preterm Infants Differ With Gestational Age

Preterm infants acquire reduced amounts of Immunoglobulin G (IgG) via trans-placental transfer as compared to term infants which might explain their high susceptibility for infections. The reduced amount of IgG antibodies also results in a lower amount of anti-inflammatory Fc N-galactosylated and -s...

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Bibliographic Details
Main Authors: Nele Twisselmann, Yannic C. Bartsch, Julia Pagel, Christian Wieg, Annika Hartz, Marc Ehlers, Christoph Härtel
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
newborn
trans-placental transfer
IgG antibodies
IgG Fc glycosylation
mothers
galactosylation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03166/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.03166/full

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