T-cells contribute to hypertension but not to renal injury in mice with subtotal nephrectomy

T-cells contribute to hypertension but not to renal injury in mice with subtotal nephrectomy

Abstract Background The pathological condition of chronic kidney disease may not be adequately recapitulated in immunocompromised mice due to the lack of T-cells, which are important for the development of hypertension and renal injury. We studied the role of the immune system in relation to salt-se...

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Bibliographic Details
Main Authors: Nynke R. Oosterhuis, Diana A. Papazova, Hendrik Gremmels, Jaap A. Joles, Marianne C. Verhaar
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Nephrology
Subjects:
Albuminuria
High salt diet
Hypertension
Subtotal nephrectomy
T-cells
Online Access:http://link.springer.com/article/10.1186/s12882-017-0555-0

Internet

http://link.springer.com/article/10.1186/s12882-017-0555-0

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