Copper-Promoted Cross-Coupling Reactions for the Synthesis of Aryl(difluoromethyl)phosphonates Using Trimethylsilyl(difluoromethyl)phosphonate

A convenient and effective route for the synthesis of aryl(difluoromethyl)phosphonates has been developed based on cross-coupling reactions. Upon treatment with a stoichiometric amount (or a catalytic amount in some cases) of CuI and CsF, aryl iodides reacted smoothly with (silyldifluoromethyl)phosp...

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Bibliographic Details
Main Authors: Kazuki Komoda, Rei Iwamoto, Masakazu Kasumi, Hideki Amii
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/23/12/3292