AMP-Activated Protein Kinase as a Reprogramming Strategy for Hypertension and Kidney Disease of Developmental Origin

AMP-Activated Protein Kinase as a Reprogramming Strategy for Hypertension and Kidney Disease of Developmental Origin

Suboptimal early-life conditions affect the developing kidney, resulting in long-term programming effects, namely renal programming. Adverse renal programming increases the risk for developing hypertension and kidney disease in adulthood. Conversely, reprogramming is a strategy aimed at reversing th...

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Bibliographic Details
Main Authors: You-Lin Tain, Chien-Ning Hsu
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:International Journal of Molecular Sciences
Subjects:
AMP-activated protein kinase
developmental origins of health and disease (DOHaD)
hypertension
kidney disease
nutrient-sensing signals
oxidative stress
renin-angiotensin system
Online Access:http://www.mdpi.com/1422-0067/19/6/1744

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http://www.mdpi.com/1422-0067/19/6/1744

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