Exercise Prevents Cardiac Injury and Improves Mitochondrial Biogenesis in Advanced Diabetic Cardiomyopathy with PGC-1α and Akt Activation

Exercise Prevents Cardiac Injury and Improves Mitochondrial Biogenesis in Advanced Diabetic Cardiomyopathy with PGC-1α and Akt Activation

Background/Aims: Diabetic cardiomyopathy (DCM) represents the major cause of morbidity and mortality among diabetics. Exercise has been reported to be effective to protect the heart from cardiac injury during the development of DCM. However, the potential cardioprotective effect of exercise in advan...

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Bibliographic Details
Main Authors: Hui Wang, Yihua Bei, Yan Lu, Wei Sun, Qi Liu, Yalong Wang, Yujie Cao, Ping Chen, Junjie Xiao, Xiangqing Kong
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
PGC-1α
Akt
Exercise
Diabetic cardiomyopathy
Mitochondria
Online Access:http://www.karger.com/Article/FullText/374021

Internet

http://www.karger.com/Article/FullText/374021

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