Cofilin/Twinstar phosphorylation levels increase in response to impaired coenzyme a metabolism.

Coenzyme A (CoA) is a pantothenic acid-derived metabolite essential for many fundamental cellular processes including energy, lipid and amino acid metabolism. Pantothenate kinase (PANK), which catalyses the first step in the conversion of pantothenic acid to CoA, has been associated with a rare neur...

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Bibliographic Details
Main Authors: Katarzyna Siudeja, Nicola A Grzeschik, Anil Rana, Jannie de Jong, Ody C M Sibon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3422318?pdf=render