Multi-modal proteomic analysis of retinal protein expression alterations in a rat model of diabetic retinopathy.

BACKGROUND: As a leading cause of adult blindness, diabetic retinopathy is a prevalent and profound complication of diabetes. We have previously reported duration-dependent changes in retinal vascular permeability, apoptosis, and mRNA expression with diabetes in a rat model system. The aim of this s...

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Bibliographic Details
Main Authors: Heather D VanGuilder, Georgina V Bixler, Lydia Kutzler, Robert M Brucklacher, Sarah K Bronson, Scot R Kimball, Willard M Freeman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3020973?pdf=render