Visual genome-wide RNAi screening to identify human host factors required for Trypanosoma cruzi infection.

The protozoan parasite Trypanosoma cruzi is the etiologic agent of Chagas disease, a neglected tropical infection that affects millions of people in the Americas. Current chemotherapy relies on only two drugs that have limited efficacy and considerable side effects. Therefore, the development of new...

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Bibliographic Details
Main Authors: Auguste Genovesio, Miriam A Giardini, Yong-Jun Kwon, Fernando de Macedo Dossin, Seo Yeon Choi, Nam Youl Kim, Hi Chul Kim, Sung Yong Jung, Sergio Schenkman, Igor C Almeida, Neil Emans, Lucio H Freitas-Junior
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3098829?pdf=render