Eph/ephrins mediated thymocyte-thymic epithelial cell interactions control numerous processes of thymus biology

Numerous studies emphasize the relevance of thymocyte-thymic epithelial cell (TECs) interactions for the functional maturation of intrathymic T lymphocytes. The tyrosine kinase receptors Ephs (Erythropoietin-producing hepatocyte kinases) and their ligands, ephrins (Eph receptor interaction proteins)...

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Bibliographic Details
Main Authors: Javier eGarcia-Ceca, David eAlfaro, Sara eMontero-Herradón, Esther eTobajas, Juan José Muñoz, Agustin G Zapata
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Immunology
Subjects:
Eph
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00333/full