Mechanical instability and titanium particles induce similar transcriptomic changes in a rat model for periprosthetic osteolysis and aseptic loosening

Wear debris particles released from prosthetic bearing surfaces and mechanical instability of implants are two main causes of periprosthetic osteolysis. While particle-induced loosening has been studied extensively, mechanisms through which mechanical factors lead to implant loosening have been less...

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Bibliographic Details
Main Authors: Mehdi Amirhosseini, Göran Andersson, Per Aspenberg, Anna Fahlgren
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Bone Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187217300219