Population-based estimate of prostate cancer risk for carriers of the HOXB13 missense mutation G84E.

Population-based estimate of prostate cancer risk for carriers of the HOXB13 missense mutation G84E.

The HOXB13 missense mutation G84E (rs138213197) is associated with increased risk of prostate cancer, but the current estimate of increased risk has a wide confidence interval (width of 95% confidence interval (CI) >200-fold) so the point estimate of 20-fold increased risk could be misleading. Po...

Full description

Bibliographic Details
Main Authors: Robert J MacInnis, Gianluca Severi, Laura Baglietto, James G Dowty, Mark A Jenkins, Melissa C Southey, John L Hopper, Graham G Giles
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3574137?pdf=render

Internet

http://europepmc.org/articles/PMC3574137?pdf=render

Similar Items