The impact of simvastatin on pulmonary effectors of Pseudomonas aeruginosa infection.

The statin family of cholesterol-lowering drugs is known to have pleiotropic properties which include anti-inflammatory and immunomodulatory effects. Statins exert their pleiotropic effects by altering expression of human immune regulators including pro-inflammatory cytokines. Previously we found th...

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Bibliographic Details
Main Authors: Emma Hennessy, Julie O'Callaghan, Marlies J Mooij, Claire Legendre, Olga Camacho-Vanegas, Sandra C Camacho, Claire Adams, John A Martignetti, Fergal O'Gara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25010049/pdf/?tool=EBI