PIK3CA hotspot mutations in circulating tumor cells and paired circulating tumor DNA in breast cancer: a direct comparison study

PIK3CA hotspot mutations in circulating tumor cells and paired circulating tumor DNA in breast cancer: a direct comparison study

Liquid biopsy analysis, mainly based on circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA), provides an extremely powerful tool for the molecular profiling of cancer patients in real time. In this study, we directly compared PIK3CA hotspot mutations (E545K, H1047R) in EpCAM‐positive CT...

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Bibliographic Details
Main Authors: Eleni Tzanikou, Athina Markou, Eleni Politaki, Anastasios Koutsopoulos, Amanda Psyrri, Dimitris Mavroudis, Vassilis Georgoulias, Evi Lianidou
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Molecular Oncology
Subjects:
breast cancer
circulating tumor cells
circulating tumor DNA
liquid biopsy
mutation analysis
PIK3CA
Online Access:https://doi.org/10.1002/1878-0261.12540

Internet

https://doi.org/10.1002/1878-0261.12540

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