On the Inhibitability of Natural Products Isolated from <i>Tetradium ruticarpum</i> towards Tyrosine Phosphatase 1B (PTP1B) and α-Glucosidase (3W37): An In Vitro and In Silico Study

On the Inhibitability of Natural Products Isolated from <i>Tetradium ruticarpum</i> towards Tyrosine Phosphatase 1B (PTP1B) and α-Glucosidase (3W37): An In Vitro and In Silico Study

Folk experiences suggest natural products in <i>Tetradium ruticarpum</i> can be effective inhibitors towards diabetes-related enzymes. The compounds were experimentally isolated, structurally elucidated, and tested in vitro for their inhibition effects on tyrosine phosphatase 1B (PTP1B)...

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Bibliographic Details
Main Authors: Dao-Cuong To, Thanh Q. Bui, Nguyen Thi Ai Nhung, Quoc-Toan Tran, Thi-Thuy Do, Manh-Hung Tran, Phan-Phuoc Hien, Truong-Nhan Ngu, Phan-Tu Quy, The-Hung Nguyen, Huu-Tho Nguyen, Tien-Dung Nguyen, Phi-Hung Nguyen
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
<i>Tetradium ruticarpum</i>
tyrosine phosphatase 1B (PTP1B)
α-glucosidase (3W37)
molecular docking simulation
Online Access:https://www.mdpi.com/1420-3049/26/12/3691

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https://www.mdpi.com/1420-3049/26/12/3691

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