Role of the Main Non HLA-Specific Activating NK Receptors in Pancreatic, Colorectal and Gastric Tumors Surveillance

Role of the Main Non HLA-Specific Activating NK Receptors in Pancreatic, Colorectal and Gastric Tumors Surveillance

Human NK cells can control tumor growth and metastatic spread thanks to their powerful cytolytic activity which relies on the expression of an array of activating receptors. Natural cytotoxicity receptors (NCRs) NKG2D and DNAM-1 are those non-HLA-specific activating NK receptors that are mainly invo...

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Bibliographic Details
Main Authors: Elisa Ferretti, Simona Carlomagno, Silvia Pesce, Letizia Muccio, Valentina Obino, Marco Greppi, Agnese Solari, Chiara Setti, Emanuela Marcenaro, Mariella Della Chiesa, Simona Sivori
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
human NK cells
NKG2D
NCR
DNAM-1
tumor escape
PDAC
Online Access:https://www.mdpi.com/2072-6694/12/12/3705

Internet

https://www.mdpi.com/2072-6694/12/12/3705

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