Energy-dependent protein folding: modeling how a protein folding machine may work [version 1; peer review: 1 approved, 2 approved with reservations]

Background: Proteins fold robustly and reproducibly in vivo, but many cannot fold in vitro in isolation from cellular components. Despite the remarkable progress that has been achieved by the artificial intelligence approaches in predicting the protein native conformations, the pathways that lead to...

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Bibliographic Details
Main Authors: Harutyun Sahakyan, Karen Nazaryan, Arcady Mushegian, Irina Sorokina
Format: Article
Language:English
Published: F1000 Research Ltd 2021-01-01
Series:F1000Research
Online Access:https://f1000research.com/articles/10-3/v1