TNF-α-Induced VEGF and MMP-9 Expression Promotes Hemorrhagic Transformation in Pituitary Adenomas

TNF-α-Induced VEGF and MMP-9 Expression Promotes Hemorrhagic Transformation in Pituitary Adenomas

Pituitary apoplexy is a clinical syndrome with unknown pathogenesis. Therefore, identifying the underlying mechanisms is of high clinical relevance. Tumor necrosis factor alpha (TNF-α) is a critical cytokine mediating various hemorrhagic events, but little is known about its involvement in pituitary...

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Bibliographic Details
Main Authors: Qin Liu, Feng Mao, Ting Lei, Jun Wu, Zhengzheng Xiao
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:International Journal of Molecular Sciences
Subjects:
pituitary apoplexy
intratumoral hemorrhage
TNF-α
VEGF
MMP-9
Online Access:http://www.mdpi.com/1422-0067/12/6/4165/

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http://www.mdpi.com/1422-0067/12/6/4165/

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