Celiac anti-type 2 transglutaminase antibodies induce phosphoproteome modification in intestinal epithelial Caco-2 cells.

BACKGROUND: Celiac disease is an inflammatory condition of the small intestine that affects genetically predisposed individuals after dietary wheat gliadin ingestion. Type 2-transglutaminase (TG2) activity seems to be responsible for a strong autoimmune response in celiac disease, TG2 being the main...

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Bibliographic Details
Main Authors: Gaetana Paolella, Ivana Caputo, Anna Marabotti, Marilena Lepretti, Anna Maria Salzano, Andrea Scaloni, Monica Vitale, Nicola Zambrano, Daniele Sblattero, Carla Esposito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3877280?pdf=render