The therapeutic effect of TBK1 in intervertebral disc degeneration via coordinating selective autophagy and autophagic functions

The therapeutic effect of TBK1 in intervertebral disc degeneration via coordinating selective autophagy and autophagic functions

Introduction: While its innate immune function has been known, recent works of literature have focused on the role of Tank binding kinase 1 (TBK1) in regulating autophagy and it is unknown whether TBK1 protects against intervertebral disc degeneration (IVDD) through affecting autophagy. Objectives:...

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Bibliographic Details
Main Authors: Sunli Hu, Liang Chen, Abdullah Al Mamun, Libin Ni, Weiyang Gao, Yan Lin, Haiming Jin, Xiaolei Zhang, Xiangyang Wang
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Journal of Advanced Research
Subjects:
TBK1
IVDD
Selective autophagy
Senescence
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123220301995

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http://www.sciencedirect.com/science/article/pii/S2090123220301995

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