Effects of CREG1 on Age-Associated Metabolic Phenotypes and Renal Senescence in Mice

Effects of CREG1 on Age-Associated Metabolic Phenotypes and Renal Senescence in Mice

Cellular repressor of E1A-stimulated genes 1 (CREG1) is a secreted glycoprotein that accelerates p16-dependent cellular senescence in vitro. We recently reported the ability of CREG1 to stimulate brown adipogenesis using adipocyte P2-CREG1-transgenic (Tg) mice; however, little is known about the eff...

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Bibliographic Details
Main Authors: Michihiro Hashimoto, Ayumi Goto, Yuki Endo, Masataka Sugimoto, Jun Ueda, Hitoshi Yamashita
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
CREG1
cellular senescence
renal dysfunction
brown adipocyte
age-related obesity
Online Access:https://www.mdpi.com/1422-0067/22/3/1276

Internet

https://www.mdpi.com/1422-0067/22/3/1276

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