mRNA induced expression of human angiotensin-converting enzyme 2 in mice for the study of the adaptive immune response to severe acute respiratory syndrome coronavirus 2.

mRNA induced expression of human angiotensin-converting enzyme 2 in mice for the study of the adaptive immune response to severe acute respiratory syndrome coronavirus 2.

The novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic. Critical to the rapid evaluation of vaccines and antivirals against SARS-CoV-2 is the development of tractable animal models to understand the adaptive immune response to the virus. To th...

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Bibliographic Details
Main Authors: Mariah Hassert, Elizabeth Geerling, E Taylor Stone, Tara L Steffen, Madi S Feldman, Alexandria L Dickson, Jacob Class, Justin M Richner, James D Brien, Amelia K Pinto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009163

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https://doi.org/10.1371/journal.ppat.1009163

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