Ethylnitrosourea induces neural progenitor cell apoptosis after S-phase accumulation in a p53-dependent manner

Neural progenitor cells populate the ventricular zone of the fetal central nervous system. In this study, immediately after the administration of ethylnitrosourea (ENU), an alkylating agent, an accumulation of neural progenitor cells in the S phase was observed. This event was caused by the inhibiti...

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Bibliographic Details
Main Authors: Kei-ichi Katayama, Masaki Ueno, Hirofumi Yamauchi, Takayuki Nagata, Hiroyuki Nakayama, Kunio Doi
Format: Article
Language:English
Published: Elsevier 2005-02-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104002281