Improved Prognostic Prediction in Never-Smoker Lung Cancer Patients by Integration of a Systemic Inflammation Marker with Tumor Immune Contexture Analysis

Improved Prognostic Prediction in Never-Smoker Lung Cancer Patients by Integration of a Systemic Inflammation Marker with Tumor Immune Contexture Analysis

Almost 25% of lung cancers (LCs) occur in never-smokers. LC inflammatory profile, based on plasma C-reactive protein levels (CRP), predicts mortality, independently by smoking-status. We hypothesized that: CRP could be associated with tumor immune contexture (TIC) in never-smokers and both these two...

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Bibliographic Details
Main Authors: Massimo Milione, Mattia Boeri, Anna Cantarutti, Giovanni Centonze, Adele Busico, Paola Suatoni, Giovanna Garzone, Laura Cattaneo, Elena Tamborini, Federica Perrone, Alessandro Mangogna, Giovanni Corrao, Giancarlo Pruneri, Gabriella Sozzi, Andrea Anichini, Ugo Pastorino
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
never-smokers
inflammation
immune profile
Online Access:https://www.mdpi.com/2072-6694/12/7/1828

Internet

https://www.mdpi.com/2072-6694/12/7/1828

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