Antitumor Activity of the Cardiac Glycoside α-L-Diginoside by Modulating Mcl-1 in Human Oral Squamous Cell Carcinoma Cells
We recently isolated a cardiac glycoside (CG), α-L-diginoside, from an indigenous plant in Taiwan, which exhibits potent tumor-suppressive efficacy in oral squamous cell carcinoma (OSCC) cell lines (SCC2095 and SCC4, IC<sub>50</sub> < 0.2 µM; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenylt...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/21/7947 |