A sustained dietary change increases epigenetic variation in isogenic mice.

Epigenetic changes can be induced by adverse environmental exposures, such as nutritional imbalance, but little is known about the nature or extent of these changes. Here we have explored the epigenomic effects of a sustained nutritional change, excess dietary methyl donors, by assessing genomic CpG...

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Bibliographic Details
Main Authors: Cheryl C Y Li, Jennifer E Cropley, Mark J Cowley, Thomas Preiss, David I K Martin, Catherine M Suter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3080854?pdf=render