Brain age prediction using deep learning uncovers associated sequence variants

Machine learning algorithms can be trained to estimate age from brain structural MRI. Here, the authors introduce a new deep-learning-based age prediction approach, and then carry out a GWAS of the difference between predicted and chronological age, revealing two associated variants.

Bibliographic Details
Main Authors: B. A. Jonsson, G. Bjornsdottir, T. E. Thorgeirsson, L. M. Ellingsen, G. Bragi Walters, D. F. Gudbjartsson, H. Stefansson, K. Stefansson, M. O. Ulfarsson
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13163-9