Binding affinity and mechanisms of SARS-CoV-2 variants

During the rapid worldwide spread of SARS-CoV-2, the viral genome has been undergoing numerous mutations, especially in the spike (S) glycoprotein gene that encode a type-I fusion protein, which plays an important role in the infectivity and transmissibility of the virus into the host cell. In this...

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Bibliographic Details
Main Authors: Yanqiang Han, Zhilong Wang, Zhiyun Wei, Igor Schapiro, Jinjin Li
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037021003160