Dietary arachidonate in milk replacer triggers dual benefits of PGE2 signaling in LPS-challenged piglet alveolar macrophages

Dietary arachidonate in milk replacer triggers dual benefits of PGE2 signaling in LPS-challenged piglet alveolar macrophages

Abstract Background Respiratory infections challenge the swine industry, despite common medicinal practices. The dual signaling nature of PGE2 (supporting both inflammation and resolution) makes it a potent regulator of immune cell function. Therefore, the use of dietary long chain n-6 PUFA to enhan...

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Bibliographic Details
Main Authors: Kathleen R. Walter, Xi Lin, Sheila K. Jacobi, Tobias Käser, Debora Esposito, Jack Odle
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Arachidonic acid
Cyclooxygenase
Eicosanoid
Eicosapentaenoic acid
Inflammation
Lipid mediator class switch
Online Access:http://link.springer.com/article/10.1186/s40104-019-0321-1

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http://link.springer.com/article/10.1186/s40104-019-0321-1

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