Clinical Features and Molecular Markers on Diffuse Midline Gliomas With H3K27M Mutations: A 43 Cases Retrospective Cohort Study

Clinical Features and Molecular Markers on Diffuse Midline Gliomas With H3K27M Mutations: A 43 Cases Retrospective Cohort Study

PurposeDiffuse midline gliomas (DMG) with H3K27M mutations have been identified as a rare distinctive entity with unique genetic features, varied molecular alterations, and poor prognosis. The current study aimed to evaluate the clinical characteristics and profile of molecular markers on patients w...

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Bibliographic Details
Main Authors: Yuan Wang, Lan-lan Feng, Pei-gang Ji, Jing-hui Liu, Shao-chun Guo, Yu-long Zhai, Eric W. Sankey, Yue Wang, Yan-rong Xue, Na Wang, Miao Lou, Meng Xu, Min Chao, Guo-Dong Gao, Yan Qu, Li Gong, Liang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
diffuse midline glioma
H3K27M
radiotherapy
P53
KPS
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.602553/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.602553/full

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