LncRNA LINC00662 promotes colon cancer tumor growth and metastasis by competitively binding with miR-340-5p to regulate CLDN8/IL22 co-expression and activating ERK signaling pathway

LncRNA LINC00662 promotes colon cancer tumor growth and metastasis by competitively binding with miR-340-5p to regulate CLDN8/IL22 co-expression and activating ERK signaling pathway

Abstract Background LncRNA LINC00662 is closely related to the occurrence and development of cancer. This study aims to explore the effect of LINC00662 on colon cancer tumor growth and metastasis and its molecular mechanism. Methods CCK8, colony formation, transwell, scratch wound, TUNEL, flow cytom...

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Bibliographic Details
Main Authors: Bo Cheng, Aimei Rong, Quanbo Zhou, Wenlu Li
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
LncRNA LINC00662
Colon cancer
miR-340-5p
CLDN8
IL22
Growth
Online Access:https://doi.org/10.1186/s13046-019-1510-7

Internet

https://doi.org/10.1186/s13046-019-1510-7

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