Non-Mendelian Dominant Maternal Effects Caused by CRISPR/Cas9 Transgenic Components in Drosophila melanogaster
The CRISPR/Cas9 system has revolutionized genomic editing. The Cas9 endonuclease targets DNA via an experimentally determined guide RNA (gRNA). This results in a double-strand break at the target site . We generated transgenic Drosophila melanogaster in which the CRISPR/Cas9 system was used to targe...
Main Authors: | Chun-Chieh Lin, Christopher J. Potter |
---|---|
Format: | Article |
Language: | English |
Published: |
Oxford University Press
2016-11-01
|
Series: | G3: Genes, Genomes, Genetics |
Subjects: | |
Online Access: | http://g3journal.org/lookup/doi/10.1534/g3.116.034884 |
Similar Items
-
CRISPR/Cas9, a universal tool for genomic engineering
by: A. V. Smirnov, et al.
Published: (2016-09-01) -
Recombinogenic activity of Pantoprazole® in somatic cells of Drosophila melanogaster
by: Jeyson Césary Lopes, et al.
Published: (2015-03-01) -
The World of Hacking: A Survey
by: Imran Memon, et al.
Published: (2020-03-01) -
Mutagenic Potential of Tetramethylthiuram Disulfide (42-S Thiram) on the Germ Cell Stages of Drosophila melanogaster
by: Lowe-Chatham, Janice E. (Janice Elaine)
Published: (1990) -
Evaluation of the mutagenic potential of Cochlospermum regium in Drosophila melanogaster male germ cells
by: Wanderlene Blanco Nunes, et al.
Published: (2003-12-01)