Bach2 overexpression represses Th9 cell differentiation by suppressing IRF4 expression in systemic lupus erythematosus

Bach2 overexpression represses Th9 cell differentiation by suppressing IRF4 expression in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by abnormal activation of T cells and caused by an imbalance in the production and clearance of apoptotic cells. We previously showed that the transcription regulator Bach2 regulated abnormal B‐cell activation in SLE. H...

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Bibliographic Details
Main Authors: Yujun Sheng, Jiali Zhang, Keke Li, Hongyan Wang, Wenjun Wang, Leilei Wen, Jinping Gao, Xianfa Tang, Huayang Tang, He Huang, Minglong Cai, Tao Yuan, Lu Liu, Xiaodong Zheng, Zhengwei Zhu, Yong Cui
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:FEBS Open Bio
Subjects:
Bach2
CD4+ T cells
IL‐9
systemic lupus erythematosus
Th9 cells
Online Access:https://doi.org/10.1002/2211-5463.13050

Internet

https://doi.org/10.1002/2211-5463.13050

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