The Inflammasome Contributes to Depletion of the Ovarian Reserve During Aging in Mice

Ovarian aging is a natural process characterized by follicular depletion and a reduction in oocyte quality, resulting in loss of ovarian function, cycle irregularity and eventually infertility and menopause. The factors that contribute to ovarian aging have not been fully characterized. Activation o...

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Bibliographic Details
Main Authors: Carolina Lliberos, Seng H. Liew, Ashley Mansell, Karla J. Hutt
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.628473/full