Symmetrical (SDMA) and asymmetrical dimethylarginine (ADMA) in sepsis: high plasma levels as combined risk markers for sepsis survival

Symmetrical (SDMA) and asymmetrical dimethylarginine (ADMA) in sepsis: high plasma levels as combined risk markers for sepsis survival

Abstract Background Nitric oxide (NO) regulates processes involved in sepsis progression, including vascular and immune function. NO is generated by nitric oxide synthases (NOS) from L-arginine. Cellular L-arginine uptake is inhibited by symmetric dimethylarginine (SDMA) and asymmetric dimethylargin...

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Bibliographic Details
Main Authors: Martin Sebastian Winkler, Axel Nierhaus, Gilbert Rösler, Susanne Lezius, Olaf Harlandt, Edzard Schwedhelm, Rainer H. Böger, Stefan Kluge
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Critical Care
Subjects:
Symmetric dimethylarginine
Asymmetric dimethylarginine
Sepsis
Online Access:http://link.springer.com/article/10.1186/s13054-018-2090-1

Internet

http://link.springer.com/article/10.1186/s13054-018-2090-1

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