Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy.

Advanced colorectal cancer (CRC) survival rates are still low despite advances in cytotoxic and targeted therapies. The development of new effective or alternative therapies is therefore urgently needed. Bromelain, an extract of pineapple, was shown to have anticancer effects, but its mechanisms in...

Full description

Bibliographic Details
Main Authors: Tung-Cheng Chang, Po-Li Wei, Precious Takondwa Makondi, Wei-Ting Chen, Chien-Yu Huang, Yu-Jia Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0210274