Considerations for clinical read alignment and mutational profiling using next-generation sequencing
Next-generation sequencing technologies are increasingly being applied in clinical settings, however the data are characterized by a range of platform-specific artifacts making downstream analysis problematic and error prone. One major application of NGS is in the profiling of clinically relevant mu...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2012-07-01
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| Series: | F1000Research |
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| Online Access: | http://f1000research.com/articles/1-2/v1 |