Pilot study of gadoxetate disodium-enhanced mri for localized and metastatic prostate cancers

Abstract OATP1B3 is expressed de novo in primary prostate cancer tissue and to a greater degree in prostate cancer metastases. Gadoxetate disodium is a substrate of OATP1B3, and its uptake has been shown to correlate with OATP1B3 expression in other cancers. We aimed to evaluate use of gadoxetate di...

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Bibliographic Details
Main Authors: Sarah E. Lochrin, Baris Turkbey, Billel Gasmi, Keith Schmidt, Jonathan D. Strope, Cindy H. Chau, Tristan M. Sissung, Douglas K. Price, Lisa Cordes, Suzana Markolovic, Bradford J. Wood, Peter A. Pinto, Yolanda L. McKinney, Joanna H. Shih, Elliot Levy, Ravi Madan, William Dahut, Peter L. Choyke, Maria Merino, William D. Figg
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84960-w