Incidence of and factors associated with false positives in laboratory diagnosis of norovirus infection by amplification of the RNA-dependent RNA polymerase gene.

BACKGROUND:Conventional reverse transcription-polymerase chain reaction (RT-PCR) amplification of the RNA-dependent RNA polymerase (RdRp) gene remains a used method for the rapid detection of norovirus (NV) in clinical laboratories. The incidence of and factors associated with false positives in thi...

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Main Authors: Fang-Ru Lin, Yu-Hua Shen, Chun-Wan Fang, Shian-Sen Shie, Chung-Guei Huang, Shuan Yang, Shu-Li Yang, Kuo-Chien Tsao, Yhu-Chering Huang, Ming-Wei Lai, Chih-Jung Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4181653?pdf=render